Description

Selected-Use-Pre-packed-Radial (SUPR) columns are pre-packed, pre-validated columns with a resin of choice.
The SUPR column range is linear scalable from lab-scale to process-scale and is available in various bed heights and column volumes. SUPR columns are ‘Plug & Process’ for direct implementation and use, ideal for campaigns and dedicated projects.

  • Large volumes, yet compact design
  • Columns can be configured to allow ‘second life’
  • Trade-in system ensures minimal downtime and ‘plug and process’ usage.
  • Full cGMP compliant pilot or process columns for fast and reproducible processing.
  • SUPR columns can be used for extended periods in campaigns or dedicated projects.
  • Reduced CAPEX by a straightforward design.
Properties
Bed volume60 ml – 600 L
Bed height3, 6, 12, 20 cm
Custom BH3 – 30 cm
MaterialsPOM, SS and PMMA
ConnectionsCustom (e.g. CPC or Tri-clamp)
SS frit GP9, 10µm, GP15, 40µm, 100µm

SUPR series – Any volume, any bed height, any resin.
The Proxcys SUPR-series are a line of compact, pre-packed chromatography columns that benefit from the full radial packed bed by superior distribution and low-pressure operation. They feature an optimized design for reduced manufacturing and material costs. SUPR columns are truly Process-ready for direct implementation and use. The columns ensure optimal process security by reproducible column performance. Proxcys will pack and validate virtually any available process resin.

All Proxcys process columns feature an internal return line, having both inlet and outlet on top for easy access. The SUPR column range is linear scalable from lab- to process-scale and is available with various bed heights and column volumes.
The SUPR column range is supplied pre-packed with a resin of choice and comes with the detailed Proxcys packing- and qualification-report.


The SUPR column design lends itself to re-use certain column parts. The Proxcys ‘Trade-In Program’ addresses cleaning and validation aspects and enables re-use of selected column parts. Allowing column parts a second life, demonstrates increase in sustainable processing and reduces ever-increasing waste streams. Once having the ‘Trade-In-Program’ integrated and aligned to usage, significant economic benefits are gained.

Based on the column usage, Proxcys Product Specialists will review how the SUPR column line and Trade-in-Program supports to achieve the Clients’ sustainability goals.

SUPR characteristics:

  • Adsorptive separations
  • Ready to Process, full cGMP compliant pilot or process columns
  • Guaranteed reproducibility
  • ISO Class 7 clean room packing (optional)
  • Highly compatible to Bio-SMB applications
  • Design optimized to reduce manufacturing cost
  • Highest throughput, largest adsorption surface area with increased dynamic binding capacity
  • Linear scalable

Same bed height and bed volume as existing process columns
By keeping identical column configuration, use of materials and principle of operation of existing validated process columns, validation steps can be accelerated significantly saving crucial time and resources. Proxcys can provide the pre-packed counterpart for any of the chromatography columns that are already being used in process by multiple pharmaceutical companies. Column packing and validation will be automated and optionally executed in ISO Class 7 clean-rooms, monitored by Proxcys experts to provide for ‘Plug and Process’ columns.

Product_overview_SUPR

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