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Human Plasma Fractionation industry
Shear sensitive, gentle, cost conscious processing
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Recombiant biopharma products
Rapid development, safe and robust
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Generics and transgenics
Fast and cost conscious processing
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Functional food industry
Easy, linear scalable to industrial size
Read the latest news
News
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Posted: March 22, 2019
Read more »A technology-oriented industry is important for the development of Drenthe. Excellent work-ethics, good education, motivated people and plenty room to develop are strong attributes that make manufacturing in Drenthe attractive. The DutchTechZone grant-initiative supports expansion and foundation of technology based companies, creating a regional technology hub. This February, Proxcys has been rewarded 90 out of 100 points by its significance for the region as member of the DutchTechZone. Proxcys is very proud to have received this recognition and is committed to grow and continue to make ‘’Made in Drenthe’’ work in the new facility that will be erected this year.
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Posted: March 04, 2019
Read more »Het is regelmatig in het nieuws. Dank zij immuuntherapie leven mensen met kanker langer met een betere kwaliteit van leven. De immuuntherapie gebruikt antilichamen (monoclonal Antibodies of mAb) zoals bijvoorbeeld alemtuzumab tegen Lymfatische leukemie of trastuzumab tegen borstkanker en maagkanker. Immuuntherapie is zeer kostbaar en de vraag laait vaak op of het aanvaardbaar is om deze therapie te vergoeden.
Met de voorgestelde cTRAC oplossing wil Proxcys een rol spelen om de productiekosten van deze kostbare therapie te verlagen met uiteindelijk het doel om de toegankelijkheid van de immuuntherapie te verbeteren. Hieronder staat een schema van een modern ‘platform’ productie proces voor de productie van antilichamen. Dit proces staat tevens model voor andere biologische productieprocessen voor medicijnen uit celkweek. In een celkweek worden micro-organismen gekweekt, die “geprogrammeerd” zijn voor het maken van bijvoorbeeld de mAb. Deze worden tijdens de productie afg -
Posted: January 25, 2019
Scalability is a valuable asset of our technology, now it is our turn. Preparations are taking shape. Plenty room for Technicians, Life-Science, Sales and Support. Proxcys = High Performance Radial Flow Chromatography (HP-RFC). In the past decade Proxcys has developed HP-RFC into a mature, efficient separation-technology and has become global market-leader to support plasma-fractionation within the Biofarma-industry. There is much more, Proxcys has developed an efficient platform for rapid, economical and sustainable isolation of monoclonal Antibodies (mAb) from high density cell culture and evolved to developed GMP-compliant custom process systems for the purification of plasma-protein, insulin and mAbs, including a wide variety of peripheral equipment. Focus always lies on process robustness, saving of (process-) time and a compact design that additionally leads to better efficiency in the occupation of cleanrooms, which strongly adds to the global sustainaRead more »
PROXCYS Downstream Biosystems
The world's primary producer of High Performance Radial Flow Chromatography (HP-RFC) equipment. PROXCYS is dedicated to develop and build cGMP purification equipment that will help to reduce the cost of life saving therapeutics.
Sustainable and industrial impact
Significant economic advantages
The compact and mobile equipment results in cleanroom volume reduction and flexible clean room planning, exceptionally well compatible with the requirements of disposable buffer systems.
Faster processing, higher throughput
Increased residence time by lower superficial velocity during critical processing steps results in fast yet gentle processing.
Low pressure drop ∆P
Lower pressure drop improves flexibility to increase process velocity for superior process economics.
Robust process technology
Process robustness of the HP-RFC technology results in superior industrial compatibility and tolerance to process errors.
Operational and process advantages
Low pressure, low shear operation
HP-RFC excels in the rapid processing of shear sensitive products with any gel or resin.
Wide product range, versatile applications
Bed height and bed volume can be chosen freely and is available in lab, pilot, process and industrial column scale with proven linear scalability between formats.
Light weighted, mobile equipment
The compact lightweight columns leave plenty space to safely maneuver equipment or disposable buffer containers within the working environment, leaving sufficient room for safe operator environment.
Non-operator dependent, reproducible results
Pairing with the Proxcys work stations, column packing and operation can be reduced to simple on-screen method selection for non-operator dependent, reproducible results.
Radial Chromatography equipment
More than a decade the unique proprietary Annular HP-RFC columns and systems help to provide column efficiency, symmetry and packed bed stability, applied in cGMP compliant purification of biologicals from various sources like Human blood plasma, cell culture, fermentation, homogenates or milk.
A large array of columns and systems cover all scales of operation, from lab bench to industrial size.
Micro columns
Mini columns
Pilot / Process columns
Industrial columns
Single Use Prepacked Radial columns (SUPR)
Packing Stations
Packing and Running stations
