Description

Mini Columns are used to closely mimic full-scale radial processes with smaller bed volumes and bed heights between 3 and 30 cm bed height. Purpose designed for versatile packing experiments. The design allows easy frit exchange for experiments with different bead sizes. The design comes with an integrated valved packing port which results in improved column performance and ensures easy handling. Flow distribution, bed heights and other physical parameters can be equal to both small scale and full radial process columns. The Mini column is specially designed for packing experiments and is often the first scale-up step.

  • Integrated valved Packing port for packing experiments
  • For column volumes between 2 - 1500 ml
  • Easy Packing port operation by turn knob
  • Self-pack or pre-packed and pre-validated
  • Linear scalable to process volumes
  • Reproducible packing and -results
  • Expected lifetime >100 packings
Properties
Bed volume20 - 1500 ml
Bed height3, 6, 12, 20 cm
Custom BH3 – 30 cm
MaterialsPOM and PMMA
ConnectionsM6, 5/16-24UNF

The Proxcys column designs are robust, resulting in exceptionally industrial compatibility since the use of Proxcys columns offers a large tolerance for errors, like accidental air, flow and pressure variations.

The Mini Column design comes with an integrated valved packing port which results in improved column performances and ensures easy handling. The clear acrylic cylinder allows to study the resin behavior and bed build-up during column packing. These choices of material together with the straight forward design reduces the learning curve, allowing you to focus on further operation and feasibility testing. Flow distribution, bed heights, frits and other physical parameters are truly equal to both small scale and full radial process columns.

Multiple Mini Chromatography columns

RFC column design lends itself perfectly for customization in terms of bed height, bed volume, frit porosities, connectors etc. Several frit porosities, to match with bead sizes between 10μm and 300μm, are available upon request. Proxcys offers resin studies to select the right frit porosity. All columns can be delivered pre-packed with resin of choice, including column qualification and packing parameters.

Fundamental attributes of the RFC Column range

  • Easy and reproducible packing
  • Custom volume and bed height
  • Lowest back pressure
  • Self-pack or pre-packed and pre-validated
  • Compatible with all resins

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