Proxcys B.V. is the world's primary producer of high performance low pressure cGMP compliant radial chromatography equipment

Micro RFC

Micro RFC columns: chromatographic performance of the radial column format in analytical scale volumes. Since the Micro RFC columns are an accurate scale-down...

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Lab HP-RFC

Lab HP-RFC columns offer “Radical” Chromatographic performance on bench scale. Ultra fast processing in robust processes with any resin and easy handling. Lab columns' suitability...
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SUPR columns

Extended range Micro to Process RFC columns in a prepacked-prevalidated format "plug-and-produce". Prepacked columns can be used for extended periods, dedicated projects...
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Pilot Process Industrial RFC

Proxcys High-Performance Radial Flow Chromatography (HP-RFC) columns are applicable from Pilot to Industrial scale operations. The "work-horses"...

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Accessories & Systems

Proxcys offers a full range of cGMP compliant accessories including sanitary Bubble traps, Intelligent packing systems and miscellaneous...
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Custom Engineering

Proxcys will develop and supply ancillary equipment that support your Downstream Processing tasks and handling. Sophisticated 3D modelling will allow fast turnaround...
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Method Development columns for HP-RFC Pilot & Process columns

Creating a scale-down model of a Pilot or Process HP-RFC column requires the most fundamental characteristics to be preserved. Expressing the radial column as a "slice column" with the same bed height, frit buildup and the same ratio between inlet & outlet opening, This will ensure the chromatographic performance similarity.

 

Also the Annular packing port position and handling are identical to their larger counterpart hence even the packing density will be very close to the full scale column it represents.

 

The radial mimic MD column can therefore be considered a true "piece of (the) cake".

 

Formats

Column Column volume (ml) Bed height (cm) Recomended Flowrates (ml/min)
CRIO-MD 61 50 6 5-75
CRIO-MD 62 125 6 15-200
CRIO-MD 63 250 6 35-400
CRIO-MD 121 100 12 5-65
CRIO-MD 122 250 12 15-150
CRIO-MD 123 500 12 35-300
CRIO-MD 181 150 18 5-60
CRIO-MD 182 375 18 15-150
CRIO-MD 183 750 18 35-300
CRIO-MD 241 200 24 5-60
CRIO-MD 242 500 24 15-150
CRIO-MD 243 1000 24 35-300

 

Applications

  • MD (Method Development) columns for bench-top process development
  • Virus clearance studies
  • Direct Capture (crude feed processing) development
  • Feasibility studies
  • Resin performance studies

 

Columns shown:

  • Series I MD Columns with 6cm, 12cm, 16cm and 30cm bed height (left)
  • Packed Series III CMD-123 MD column 12cm bed height 500ml Bed volume (middle)
  • Series I MD Columns with 6cm, 12cm, 16cm and 30cm bed height (right)

 

Included:

  • MD columns are supplied with CPC quick connect fittings, basic tubing kit and user manual.
  • MD columns feature an integrated CRIO-Annular mimic packing port for facilitated handling.

 

Proxcys B.V. is the world's primary producer of high performance low pressure cGMP compliant radial chromatography equipment.

Contact

Proxcys BV

Bedrijvenweg 4

NL-7833 JH Nieuw-Amsterdam

The Netherlands

Phone: +31 591 677 447

Fax: +31 591 677 448

Email: info@proxcys.com